LGK-974
Product Specifications
CAS Number
1243244-14-5
Synonyms
NVP-LGK974, WNT974
Target
PORCN
Applications
Cytoskeletal Signaling
Smiles
CC1=CC (=CN=C1C2=CC (=NC=C2) C) CC (=O) NC3=NC=C (C=C3) C4=NC=CN=C4
Molecular Formula
C23H20N6O
Additionnal Information
LGK-974 (NVP-LGK974, WNT974) is a potent and specific PORCN inhibitor, and inhibits Wnt signaling with IC50 of 0.4 nM in TM3 cells. Phase 1.
Storage Conditions
2 years -80 in solvent
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