(+) -JQ1
Product Specifications
CAS Number
1268524-70-4
Target
Epigenetic Reader Domain
Applications
Epigenetics
Smiles
CC1=C (SC2=C1C (=NC (C3=NN=C (N32) C) CC (=O) OC (C) (C) C) C4=CC=C (C=C4) Cl) C
Molecular Formula
C23H25ClN4O2S
Additionnal Information
(+) -JQ1 is a BET bromodomain inhibitor, with IC50 of 77 nM/33 nM for BRD4 (1/2) in cell-free assays, binding to all bromodomains of the BET family, but not to bromodomains outside the BET family. (+) -JQ1 suppresses cell proliferation via inducing autophagy. (+) -JQ1 inhibits the expression of Nuclear receptor binding SET domain protein 3 (NSD3) target genes.
Storage Conditions
2 years -80 in solvent
More Discoveries
Explore Other Products
Browse additional items from our catalog
NB500-580G 0.1 mL
Rabbit Polyclonal Kinesin 5B Antibody [DyLight 488]
Sign In for Pricing
View Details 
RR213035L3V 200 µL
Phf7 (NM_001012211) Rat Tagged ORF Clone Lentiviral Particle
Sign In for Pricing
View Details 