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AZD1208

Product Specifications

CAS Number

1204144-28-4

Target

Pim

Applications

JAK/STAT

Smiles

C1CC (CN (C1) C2=C (C=CC=C2C3=CC=CC=C3) C=C4C (=O) NC (=O) S4) N

Molecular Formula

C21H21N3O2S

Additionnal Information

AZD1208 is a potent, and orally available Pim kinase inhibitor with IC50 of 0.4 nM, 5 nM, and 1.9 nM for Pim1, Pim2, and Pim3 in cell-free assays, respectively. AZD1208 induces autophagy, cell cycle arrest and apoptosis. Phase 1.

Storage Conditions

2 years -80 in solvent

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