WEHI-539
Product Specifications
CAS Number
1431866-33-9
Target
Bcl-2
Applications
Apoptosis
Smiles
C1CC2=C (C=C (C=C2) C3=NC (=C (S3) CCCOC4=CC=C (C=C4) CN) C (=O) O) C (=NNC5=NC6=CC=CC=C6S5) C1.Cl
Molecular Formula
C31H29N5O3S2
Additionnal Information
WEHI-539 has high affinity (IC50=1.1 nM) and selectivity for BCL-XL and potently kills cells by selectively antagonizing its prosurvival activity. It has more than a 400-fold higher affinity for BCL-XL versus other prosurvival BCL-2 family members.
Storage Conditions
2 years -80 in solvent
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