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PF-3758309

Product Specifications

CAS Number

898044-15-0

Synonyms

PF-03758309

Target

PAK

Applications

Cytoskeletal Signaling

Smiles

CC1=NC2=C (C (=N1) NC3=NNC4=C3CN (C4 (C) C) C (=O) NC (CN (C) C) C5=CC=CC=C5) SC=C2

Molecular Formula

C25H30N8OS

Additionnal Information

PF-03758309 (PF-03758309) is a potent, ATP-competitive, pyrrolopyrazole inhibitor of PAK4 with Kd of 2.7 nM. PF-3758309 is antiproliferative and induces apoptosis in a HCT116 tumor model.

Storage Conditions

2 years -80 in solvent

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