PF-3758309
Product Specifications
CAS Number
898044-15-0
Synonyms
PF-03758309
Target
PAK
Applications
Cytoskeletal Signaling
Smiles
CC1=NC2=C (C (=N1) NC3=NNC4=C3CN (C4 (C) C) C (=O) NC (CN (C) C) C5=CC=CC=C5) SC=C2
Molecular Formula
C25H30N8OS
Additionnal Information
PF-03758309 (PF-03758309) is a potent, ATP-competitive, pyrrolopyrazole inhibitor of PAK4 with Kd of 2.7 nM. PF-3758309 is antiproliferative and induces apoptosis in a HCT116 tumor model.
Storage Conditions
2 years -80 in solvent
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