Ceritinib
Product Specifications
CAS Number
1032900-25-6
Synonyms
LDK378
Target
ALK
Applications
Protein Tyrosine Kinase
Smiles
CC1=CC (=C (C=C1C2CCNCC2) OC (C) C) NC3=NC=C (C (=N3) NC4=CC=CC=C4S (=O) (=O) C (C) C) Cl
Molecular Formula
C28H36ClN5O3S
Additionnal Information
Ceritinib is a potent inhibitor against ALK with IC50 of 0.2 nM in cell-free assays. Ceritinib (LDK378) also inhibits IGF-1R, InsR, STK22D and FLT3 with IC50 of 8 nM, 7 nM, 23 nM and 60 nM, respectively. Phase 3.
Storage Conditions
2 years -80 in solvent
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