SGC 0946
Product Specifications
CAS Number
1561178-17-3
Target
Histone Methyltransferase
Applications
Epigenetics
Smiles
CC (C) N (CCCNC (=O) NC1=CC=C (C=C1) C (C) (C) C) CC2C (C (C (O2) N3C=C (C4=C (N=CN=C43) N) Br) O) O
Molecular Formula
C28H40BrN7O4
Additionnal Information
SGC 0946 is a highly potent and selective DOT1L methyltransferase inhibitor with IC50 of 0.3 nM in a cell-free assay, is inactive against a panel of 12 PMTs and DNMT1.
Storage Conditions
2 years -80 in solvent
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