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Cilengitide trifluoroacetate

Product Specifications

CAS Number

199807-35-7

Synonyms

EMD 121974, NSC 707544

Target

Integrin

Applications

Cytoskeletal Signaling

Smiles

CC (C) C1C (=O) NC (C (=O) NCC (=O) NC (C (=O) NC (C (=O) N1C) CC2=CC=CC=C2) CC (=O) O) CCCN=C (N) N.C (=O) (C (F) (F) F) O

Molecular Formula

C29H41F3N8O9

Additionnal Information

Cilengitide (EMD 121974, NSC 707544) is a potent integrin inhibitor for αvβ3 receptor and αvβ5 receptor with IC50 of 4.1 nM and 79 nM in cell-free assays, respectively; ~10-fold selectivity against gpIIbIIIa. Phase 2.

Storage Conditions

2 years -80 in solvent

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