T0901317
Product Specifications
CAS Number
293754-55-9
Target
Liver X Receptor
Applications
Metabolism
Smiles
C1=CC=C (C=C1) S (=O) (=O) N (CC (F) (F) F) C2=CC=C (C=C2) C (C (F) (F) F) (C (F) (F) F) O
Molecular Formula
C17H12F9NO3S
Additionnal Information
T0901317 is a potent and selective agonist for both LXR and FXR, with EC50 of 20nM for LXRα and 5 μM for FXR, respectively. T0901317 is a dual inverse agonist of RORα and RORγ with Ki of 132 nM and 51 nM, respectively. T0901317 significantly suppresses cell proliferation and induces apoptosis.
Storage Conditions
2 years -80 in solvent
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