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T0901317

Product Specifications

CAS Number

293754-55-9

Target

Liver X Receptor

Applications

Metabolism

Smiles

C1=CC=C (C=C1) S (=O) (=O) N (CC (F) (F) F) C2=CC=C (C=C2) C (C (F) (F) F) (C (F) (F) F) O

Molecular Formula

C17H12F9NO3S

Additionnal Information

T0901317 is a potent and selective agonist for both LXR and FXR, with EC50 of 20nM for LXRα and 5 μM for FXR, respectively. T0901317 is a dual inverse agonist of RORα and RORγ with Ki of 132 nM and 51 nM, respectively. T0901317 significantly suppresses cell proliferation and induces apoptosis.

Storage Conditions

2 years -80 in solvent

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