GSK J4 HCl
Product Specifications
CAS Number
1797983-09-5
Target
Histone Demethylase
Applications
Epigenetics
Smiles
CCOC (=O) CCNC1=CC (=NC (=N1) C2=CC=CC=N2) N3CCC4=CC=CC=C4CC3.Cl
Molecular Formula
C24H27N5O2.HCl
Additionnal Information
GSK J4 HCl is a cell permeable prodrug of GSK J1, which is the first selective inhibitor of the H3K27 histone demethylase JMJD3 and UTX with IC50 of 60 nM in a cell-free assay and inactive against a panel of demethylases of the JMJ family.
Storage Conditions
2 years -80 in solvent
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