Tepotinib

Product Specifications

CAS Number

1100598-32-0

Synonyms

EMD 1214063, MSC2156119

Target

C-Met

Applications

Protein Tyrosine Kinase

Smiles

CN1CCC (CC1) COC2=CN=C (N=C2) C3=CC=CC (=C3) CN4C (=O) C=CC (=N4) C5=CC=CC (=C5) C#N

Molecular Formula

C29H28N6O2

Additionnal Information

Tepotinib is a potent and selective c-Met inhibitor with IC50 of 4 nM, >200-fold selective for c-Met than IRAK4, TrkA, Axl, IRAK1, and Mer. Tepotinib (EMD 1214063) induces autophagy. Phase 1.

Storage Conditions

2 years -80 in solvent

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