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Oprozomib

Product Specifications

CAS Number

935888-69-0

Synonyms

ONX 0912, PR-047

Target

Proteasome

Applications

Proteases

Smiles

CC1=NC=C (S1) C (=O) NC (COC) C (=O) NC (COC) C (=O) NC (CC2=CC=CC=C2) C (=O) C3 (CO3) C

Molecular Formula

C25H32N4O7S

Additionnal Information

Oprozomib is an orally bioavailable inhibitor for CT-L activity of 20S proteasome β5/LMP7 with IC50 of 36 nM/82 nM. Phase 1/2.

Storage Conditions

2 years -80 in solvent

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