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Talazoparib (BMN 673)

Product Specifications

CAS Number

1207456-01-6

Synonyms

LT-673

Target

PARP

Applications

DNA Damage/DNA Repair

Smiles

CN1C (=NC=N1) C2C (NC3=CC (=CC4=C3C2=NNC4=O) F) C5=CC=C (C=C5) F

Molecular Formula

C19H14F2N6O

Additionnal Information

Talazoparib (BMN 673, LT-673) is a novel PARP inhibitor with IC50 of 0.57 nM for PARP1 in a cell-free assay. It is also a potent inhibitor of PARP-2, but does not inhibit PARG and is highly sensitive to PTEN mutation. Phase 3.

Storage Conditions

2 years -80 in solvent

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