BAY 1000394
Product Specifications
CAS Number
1223498-69-8
Synonyms
Roniciclib
Target
CDK
Applications
Cell Cycle
Molecular Formula
C18H21F3N4O3S
Additionnal Information
BAY 1000394 (Roniciclib) is a potent inhibitor of pan-CDK, that inhibits the kinase activity of the cell-cycle cyclin-dependent kinases (CDKs), with IC50 of 7, 9, 11, 25 and 5 nmol/L for CDK1, CDK2, CDK4, CDK7 and CDK9, respectively. It induces cell-cycle arrest and apoptosis and exhibits potent antitumor activity.
Storage Conditions
2 years -80 in solvent
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