Brefeldin A (BFA)
Product Specifications
CAS Number
20350-15-6
Synonyms
Cyanein, Decumbin
Target
ATPase
Applications
Transmembrane Transporters
Smiles
CC1CCCC=CC2CC (CC2C (C=CC (=O) O1) O) O
Molecular Formula
C16H24O4
Additionnal Information
Brefeldin A (BFA) is a lactone antibiotic and ATPase inhibitor for protein transport with IC50 of 0.2 μM in HCT 116 cells, induces cancer cell differentiation and apoptosis. It could also improve the HDR (homology-directed repair) efficiency and be an enhancer of CRISPR-mediated HDR. Brefeldin A is also an inhibitor of autophagy and mitophagy.
Storage Conditions
2 years -80 in solvent
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