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Ko143

Product Specifications

CAS Number

461054-93-3

Target

BCRP

Applications

Transmembrane Transporters

Smiles

CC (C) CC1C2=C (CC3N1C (=O) C (NC3=O) CCC (=O) OC (C) (C) C) C4=C (N2) C=C (C=C4) OC

Molecular Formula

C26H35N3O5

Additionnal Information

KO143 is a potent and relatively selective ATP-binding cassette sub-family G member 2 (ABCG2/BCRP) inhibitor. KO143 decreases the ATPase activity of ABCG2 with IC50 of 9.7 nM.

Storage Conditions

3 years -20°C powder

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