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XL019

Product Specifications

CAS Number

945755-56-6

Target

JAK

Applications

Angiogenesis

Smiles

C1CC (NC1) C (=O) NC2=CC=C (C=C2) C3=NC (=NC=C3) NC4=CC=C (C=C4) N5CCOCC5

Molecular Formula

C25H28N6O2

Additionnal Information

XL019 is a potent and selective JAK2 inhibitor with IC50 of 2.2 nM, exhibiting >50-fold selectivity over JAK1, JAK3 and TYK2. Phase 1.

Storage Conditions

2 years -80 in solvent

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