Birinapant

Product Specifications

CAS Number

1260251-31-7

Synonyms

TL32711

Target

IAP

Applications

Apoptosis

Smiles

CCC (C (=O) N1CC (CC1CC2=C (NC3=C2C=CC (=C3) F) C4=C (C5=C (N4) C=C (C=C5) F) CC6CC (CN6C (=O) C (CC) NC (=O) C (C) NC) O) O) NC (=O) C (C) NC

Molecular Formula

C42H56F2N8O6

Additionnal Information

Birinapant is a SMAC mimetic antagonist, mostly to cIAP1 with Kd of <1 nM in a cell-free assay, less potent to XIAP. Birinapant helps to induce apoptosis in latent HIV-1-infected cells. Phase 2.

Storage Conditions

2 years -80 in solvent

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