(+) -JQ1 carboxylic acid

(+) -JQ1 carboxylic acid ((+) -JQ1-COOH) is a (+) -JQ1 with a carboxylic acid functional group. (+) -JQ1 carboxylic acid ((+) -JQ1-COOH) can be used as a precursor to a PROTAC that targets BET bromodomains after conjugation to a linker and E3 ligase ligand.