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VU0071063

Product Specifications

CAS Number

333415-38-6

Target

Potassium Channel

Applications

Transmembrane Transporters

Smiles

CN1C (=O) N (C) C2=C ([N] (CC3=CC=C (C=C3) C (C) (C) C) C=N2) C1=O

Molecular Formula

C18H22N4O2

Additionnal Information

VU0071063 activates heterologously expressed Kir6.2/SUR1 channels with a EC50 of 7 μM, dose dependently and reversibly hyperpolarizes the β-cell membrane potential, which, in turn, inhibits glucose-stimulated Ca2+ entry and insulin secretion.

Storage Conditions

3 years -20°C powder

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