APTO-253
Product Specifications
CAS Number
916151-99-0
Synonyms
LOR-253, LT-253
Target
Myc
Applications
Apoptosis
Smiles
CC1=C (C2=NC3=C ([NH]2) C4=CC=CN=C4C5=C3C=CC=N5) C6=C ([NH]1) C=CC (=C6) F
Molecular Formula
C22H14FN5
Additionnal Information
APTO-253 (LOR-253, LT-253) inhibits c-Myc expression and selectively induces CDKN1A (p21), promotes G0-G1 cell-cycle arrest, and triggers apoptosis in acute myeloid leukemia (AML) cells. APTO-253 is also an inducer of KLF4 (Krüppel-like factor 4) .
Storage Conditions
3 years -20°C powder
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