TPEN
Product Specifications
CAS Number
16858-02-9
Synonyms
TPEDA
Target
Apoptosis related
Applications
Apoptosis
Smiles
C (CN (CC1=NC=CC=C1) CC2=NC=CC=C2) N (CC3=NC=CC=C3) CC4=NC=CC=C4
Molecular Formula
C26H28N6
Additionnal Information
TPEN (TPEDA) is a specific cell-permeable heavy metal chelator that induces apoptosis in NB4 cells via negatively regulating intracellular NO and Zn2+ signaling. TPEN (TPEDA) may be a potential therapeutic strategy for APL (acute promyelocytic leukemia) .TPEN induces DNA damage and increases intracellular ROS production and also inhibits cell proliferation.
Storage Conditions
3 years -20°C powder
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