GW406108X
Product Specifications
CAS Number
1644443-92-4
Synonyms
GW108X
Target
Kinesin
Applications
Cytoskeletal Signaling
Smiles
OC1=C (Cl) C=C (C=C1Cl) /C=C/2C (=O) NC3=C2C=C (C=C3) C (=O) C4=CC=CO4
Molecular Formula
C20H11Cl2NO4
Additionnal Information
GW406108X (GW108X) is an inhibitor of Kif15 (Kinesin-12) with an IC50 of 0.82 μM in the ATPase assay. GW406108X inhibits recombinant ULK1 kinase activity with a pIC50 of 6.37 and blocks autophagy in cells, without affecting the upstream signalling kinases mTORC1 and AMPK.
Storage Conditions
3 years -20°C powder
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