MK-28
Product Specifications
CAS Number
864388-65-8
Target
PERK
Applications
Apoptosis
Molecular Formula
C24H20N4O2
Additionnal Information
MK-28 is a potent and selective activator of PERK. MK-28 exhibits an IC50 ~3-fold higher than CCT020312 in rescuing mutant huntingtin protein (mHtt) -expressing striatal neurons from apoptosis. MK-28 exhibits remarkable pharmacokinetic properties and high BBB penetration in mice.
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