Gap19
Product Specifications
CAS Number
1507930-57-5
Target
Gap-Junction
Applications
Cytoskeletal Signaling
Smiles
CCC (C) C (NC (=O) C (CCC (O) =O) NC (=O) C (NC (=O) C (CCC (N) =O) NC (=O) C (N) CCCCN) C (C) CC) C (=O) NC (CCCCN) C (=O) NC (CCCCN) C (=O) NC (CC1=CC=CC=C1) C (=O) NC (CCCCN) C (O) =O
Molecular Formula
C55H96N14O13
Additionnal Information
Gap19 is a nonapeptide derived from the cytoplasmic loop (CL) of Cx43 and acts as a selective connexin 43 (Cx43) hemichannel blocker. Gap19 blocks Cx43 hemichannels without inhibiting gap junctions (GJs) at IC50 of 6.5 μM when applied intracellulary.
Storage Conditions
3 years -20°C powder
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