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Gap19

Product Specifications

CAS Number

1507930-57-5

Target

Gap-Junction

Applications

Cytoskeletal Signaling

Smiles

CCC (C) C (NC (=O) C (CCC (O) =O) NC (=O) C (NC (=O) C (CCC (N) =O) NC (=O) C (N) CCCCN) C (C) CC) C (=O) NC (CCCCN) C (=O) NC (CCCCN) C (=O) NC (CC1=CC=CC=C1) C (=O) NC (CCCCN) C (O) =O

Molecular Formula

C55H96N14O13

Additionnal Information

Gap19 is a nonapeptide derived from the cytoplasmic loop (CL) of Cx43 and acts as a selective connexin 43 (Cx43) hemichannel blocker. Gap19 blocks Cx43 hemichannels without inhibiting gap junctions (GJs) at IC50 of 6.5 μM when applied intracellulary.

Storage Conditions

3 years -20°C powder

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