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Brevilin A

Product Specifications

CAS Number

16503-32-5

Synonyms

6-O-Angeloylplenolina

Target

STAT

Applications

Apoptosis

Molecular Formula

C20H26O5

Additionnal Information

Brevilin A (6-O-Angeloylplenolina), a sesquiterpene lactone isolated from Centipeda minima, is a selective inhibitor of STAT3 and attenuates the JAKs activity by blocking the JAKs tyrosine kinase domain JH1. Brevilin A induces apoptosis and autophagy of colon adenocarcinoma cell CT26 via mitochondrial pathway and PI3K/AKT/mTOR inactivation.

Storage Conditions

3 years -20°C powder

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