Brevilin A
Product Specifications
CAS Number
16503-32-5
Synonyms
6-O-Angeloylplenolina
Target
STAT
Applications
Apoptosis
Molecular Formula
C20H26O5
Additionnal Information
Brevilin A (6-O-Angeloylplenolina), a sesquiterpene lactone isolated from Centipeda minima, is a selective inhibitor of STAT3 and attenuates the JAKs activity by blocking the JAKs tyrosine kinase domain JH1. Brevilin A induces apoptosis and autophagy of colon adenocarcinoma cell CT26 via mitochondrial pathway and PI3K/AKT/mTOR inactivation.
Storage Conditions
3 years -20°C powder
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