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Vacuolin-1

Product Specifications

CAS Number

351986-85-1

Target

PIKfyve

Applications

PI3K/Akt/mTOR

Smiles

IC1=CC=CC (=C1) /C=N/NC2=NC (=NC (=N2) N (C3=CC=CC=C3) C4=CC=CC=C4) N5CCOCC5

Molecular Formula

C26H24IN7O

Additionnal Information

Vacuolin-1 is a potent and cell-permeable inhibitor that blocks the Ca (2+) -dependent exocytosis of lysosomes and prevents the release of lysosomal content without affecting the process of resealing. Vacuolin-1 is also a potent and selective PIKfyve inhibitor, and inhibits autophagy by impairing lysosomal maturation via PIKfyve inhibition.

Storage Conditions

3 years -20°C powder

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