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Epertinib hydrochloride

Product Specifications

CAS Number

2071195-74-7

Synonyms

Epertinib HCl, S-222611 hydrochloride, S-222611 HCl

Target

EGFR

Applications

Protein Tyrosine Kinase

Smiles

Cl.CC#CC (=N\OCC1COCCN1) /C2=CC3=C (C=C2) N=CN=C3NC4=CC=C (OCC5=CC (=CC=C5) F) C (=C4) Cl

Molecular Formula

C30H28Cl2FN5O3

Additionnal Information

Epertinib hydrochloride (S-222611 hydrochloride) is a potent, orally active, reversible, and selective tyrosine kinase inhibitor of EGFR, HER2 and HER4 with IC50 of 1.48 nM, 7.15 nM and 2.49 nM, respectively. Epertinib hydrochloride (S-222611 hydrochloride) exhibits antitumor activity.

Storage Conditions

3 years -20°C powder

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