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HI-TOPK-032

Product Specifications

CAS Number

487020-03-1

Target

TOPK

Applications

MAPK

Smiles

C1=CC=C2C (=C1) N=C3C (=C4C=C (C=CN4C3=N2) NC (=O) C5=CC=CS5) C#N

Molecular Formula

C20H11N5OS

Additionnal Information

HI-TOPK-032 is a potent and specific inhibitor of TOPK. HI-TOPK-032 also reduces ERK-RSK phosphorylation, regulates of the abundance of p53, cleaved caspase-7, and cleaved PARP, and induces apoptosis in cancer cells.

Storage Conditions

3 years -20°C powder

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