JND3229
Product Specifications
CAS Number
2260886-64-2
Target
EGFR
Applications
Protein Tyrosine Kinase
Smiles
CCC (=O) NC1CCC (CC1) N2C3=NC (=NC=C3CN (C2=O) C4=CC=CC=C4Cl) NC5=CC (=C (C=C5) N6CCN (CC6) C) C
Molecular Formula
C33H41ClN8O2
Additionnal Information
JND3229 is a potent reversible inhibitor of EGFRC797S with an IC50 value of 5.8 nM. JND3229 also potently suppresses EGFRL858R/T790M and EGFRWT with IC50 values of 30.5 nM and 6.8 nM, respectively.
Storage Conditions
3 years -20°C powder
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