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3'-Fluoro-3'-deoxythymidine (Alovudine)

Product Specifications

CAS Number

25526-93-6

Synonyms

CL 184824, FddThd, FLT, MIV-310

Target

Reverse Transcriptase

Applications

Microbiology

Smiles

CC1=CN (C (=O) NC1=O) C2CC (C (O2) CO) F

Molecular Formula

C10H13FN2O4

Additionnal Information

3'-Fluoro-3'-deoxythymidine (Alovudine, CL 184824, FddThd, FLT, MIV-310) is a potent inhibitor of polymerase γ and reverse transcriptase that can be used in the treatment of HIV infection. 3'-Fluoro-3'-deoxythymidine (Alovudine) is also a marker of DNA synthesis that can be used as an early response biomarker in the chemotherapy of pancreatic cancer.

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