3'-Fluoro-3'-deoxythymidine (Alovudine)
Product Specifications
CAS Number
25526-93-6
Synonyms
CL 184824, FddThd, FLT, MIV-310
Target
Reverse Transcriptase
Applications
Microbiology
Smiles
CC1=CN (C (=O) NC1=O) C2CC (C (O2) CO) F
Molecular Formula
C10H13FN2O4
Additionnal Information
3'-Fluoro-3'-deoxythymidine (Alovudine, CL 184824, FddThd, FLT, MIV-310) is a potent inhibitor of polymerase γ and reverse transcriptase that can be used in the treatment of HIV infection. 3'-Fluoro-3'-deoxythymidine (Alovudine) is also a marker of DNA synthesis that can be used as an early response biomarker in the chemotherapy of pancreatic cancer.
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