GRL0617
Product Specifications
CAS Number
1093070-16-6
Target
DUB
Applications
Ubiquitin
Smiles
CC1=C (C=C (C=C1) N) C (=O) NCCC2=CC=CC3=CC=CC=C32
Molecular Formula
C20H20N2O
Additionnal Information
GRL0617 is a potent, selective and competitive noncovalent inhibitor of severe acute respiratory syndrome (SARS-CoV) papain-like protease (PLPro) /deubiquitinase with IC50 of 0.6 μM and Ki of 0.49 μM. GRL0617 inhibits SARS-CoV viral replication in Vero E6 cells with EC50 of 15 microM and has no associated cytotoxicity.
Storage Conditions
3 years -20°C powder
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