RU.521
Product Specifications
CAS Number
2262452-06-0
Synonyms
RU320521
Target
CGAS
Applications
Autophagy
Smiles
CC1=C (C (=O) N (N1) C2=NC3=C (N2) C=CC (=C3Cl) Cl) C4C5=CC=CC=C5C (=O) O4
Molecular Formula
C19H12Cl2N4O3
Additionnal Information
RU.521 (RU320521) is an active, potent and selective inhibitor of cyclic GMP-AMP synthase (cGAS) that inhibits the cGAS-mediated signaling with IC50 of 700 nM. RU.521 binds to the cGAS/dsDNA complex with Kd of 36.2 nM.
Storage Conditions
3 years -20°C powder
More Discoveries
Explore Other Products
Browse additional items from our catalog
ARP36119_T100-HRP 100 µL
ZFP91 Antibody - N-terminal region : HRP (ARP36119_T100-HRP)
Sign In for Pricing
View Details MBS6240741-01 0.1 mL
SPP1 (Secreted Phosphoprotein 1, BNSP, BSPI, ETA-1, MGC110940, OPN) (MaxLight 750)
Sign In for Pricing
View Details MBS6240741-02 5x 0.1 mL
SPP1 (Secreted Phosphoprotein 1, BNSP, BSPI, ETA-1, MGC110940, OPN) (MaxLight 750)
Sign In for Pricing
View Details