DIM-C-pPhOH
Product Specifications
CAS Number
151358-47-3
Synonyms
C-DIM8, CDIM8
Target
Nur77
Applications
Apoptosis
Smiles
C1=CC=C2C (=C1) C (=CN2) C (C3=CC=C (C=C3) O) C4=CNC5=CC=CC=C54
Molecular Formula
C23H18N2O
Additionnal Information
DIM-C-pPhOH (C-DIM8, CDIM8) is a nuclear receptor 4A1 (NR4A1) (Nur77) antagonist. DIM-C-pPhOH inhibits tumor growth and mTOR signaling, induces apoptosis and cellular stress. DIM-C-pPhOH reduces cell proliferation with IC50 of 13.6 μM and 13.0 μM for ACHN cells and 786-O cells, respectively.
Storage Conditions
3 years -20°C powder
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