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Ellipticine hydrochloride

Product Specifications

CAS Number

5081-48-1

Synonyms

NSC 71795 hydrochloride, PZE

Target

P450 (e.g. CYP17)

Applications

Metabolism

Smiles

CC1=C2C=CN=CC2=C (C3=C1NC4=CC=CC=C43) C.Cl

Molecular Formula

C17H15ClN2

Additionnal Information

Ellipticine Hydrochloride (NSC 71795, PZE) is a potent inhibitor of DNA topoisomerase II and forms covalent DNA adducts mediated by its oxidation with cytochromes P450 (CYP) and peroxidases. Ellipticine Hydrochloride is a natural product isolated from the Australian evergreen tree of the Apocynaceae family with antineoplastic activity.

Storage Conditions

3 years -20°C powder

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