RSV L-protein-IN-1
RSV L-protein-IN-1 (compound D) is a potent inhibitor of Respiratory syncytial virus (RSV) (EC50=0.021 μM) . RSV L-protein-IN-1 inhibits Polymerase (IC50=0.089 μM), and blocks RSV mRNA synthesis by inhibiting guanylation of viral transcripts. RSV L-protein-IN-1 shows moderate cytotoxicity (CC50=8.4 μM, HEp-2), also exhibits activity and lowers virus titers in mouse models of RSV infection[1].
Product Specifications
CAS Number
[851658-10-1]
UNSPSC
12352005
Target
RSV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/rsv-l-protein-in-1.html
Purity
98.09
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(C(C)(C)C1=C2C3=C(NC(C4=CC=C(C)C([N+]([O-])=O)=C4)=N3)C(N)=C1)N(CCCNCCC5=CC=C(OC)C(OC)=C5)C2=O
Molecular Formula
C32H36N6O6
Molecular Weight
600.66
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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