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TM5441

Product Specifications

CAS Number

1190221-43-2

Target

PAI-1

Applications

Metabolism

Smiles

C1=CC (=CC (=C1) NC (=O) COCC (=O) NC2=C (C=C (C=C2) Cl) C (=O) O) C3=COC=C3

Molecular Formula

C21H17ClN2O6

Additionnal Information

TM5441 is an orally bioavailable inhibitor of plasminogen activator inhibitor-1 (PAI-1) with IC50 ranging between 9.7 μM and 60.3 μM. TM5441 induces intrinsic apoptosis in several human cancer cell lines.

Storage Conditions

3 years -20°C powder

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