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DM1 (Mertansine)

Product Specifications

CAS Number

139504-50-0

Synonyms

Maytansinoid DM1

Target

Microtubule Associated

Applications

Cytoskeletal Signaling

Smiles

COC1\C=C\C=C (C) \CC2=CC (=C (Cl) C (=C2) OC) N (C) C (=O) CC (OC (=O) C (C) N (C) C (=O) CCS) C3 (C) OC3C (C) C4CC1 (O) NC (=O) O4

Molecular Formula

C35H48ClN3O10S

Additionnal Information

DM1 (Mertansine), an antibody-conjugatable maytansinoid, is a selective microtubule inhibitor that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery. Mertansine can be attached to a monoclonal antibody with a linker to create an antibody-drug conjugate (ADC) .Solutions are unstable and should be fresh-prepared.

Storage Conditions

3 years -20°C powder

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