TQB3804
Product Specifications
CAS Number
2267329-76-8
Synonyms
EGFR-IN-7
Target
EGFR
Applications
Protein Tyrosine Kinase
Smiles
CC1=CC (=C (C=C1N2CCC (CC2) N3CCN (CC3) C) OC) NC4=NC=C (C (=N4) NC5=C (C6=NC=CN=C6C=C5) P (=O) (C) C) Br
Molecular Formula
C32H41BrN9O2P
Additionnal Information
TQB3804 is a selective and potent EGFR kinase inhibitor with IC50 of 0.46 nM, 0.13 nM, 0.26 nM, 0.19 nM and 1.07 nM for for EGFRd746-750/T790M/C797S, EGFRL858R/T790M/C797S, EGFRd746-750/T790M, EGFRL858R/T790M and EGFRWT, respectively. TQB3804 (EGFR-IN-7) shows anti-tumor activity.
Storage Conditions
3 years -20°C powder
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