C25-140
Product Specifications
CAS Number
1358099-18-9
Target
NF-κB
Applications
NF-κB
Smiles
CC1=C (C (=NN1C2=NN3C (=NN=C3C=C2) C) C) CCC (=O) N4CCC (CC4) CC5=CC=CC=C5
Molecular Formula
C26H31N7O
Additionnal Information
C25-140 is a small-molecule inhibitor of TRAF6-Ubc13 interaction. C25-140 directly binds to TRAF6, thereby blocking the interaction of TRAF6 with Ubc13, and as a consequence lowers TRAF6 activity. C25-140 impedes NF-κB activation in various immune and inflammatory signaling pathways also in primary human and murine cells.
Storage Conditions
3 years -20°C powder
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