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Resmetirom (MGL-3196)

Product Specifications

CAS Number

920509-32-6

Synonyms

VIA-3196

Target

THR

Applications

Endocrinology & Hormones

Smiles

CC (C) C1=CC (=NNC1=O) OC2=C (C=C (C=C2Cl) N3C (=O) NC (=O) C (=N3) C#N) Cl

Molecular Formula

C17H12Cl2N6O4

Additionnal Information

Resmetirom (MGL-3196, VIA-3196) is a liver-directed, orally active, selective thyroid hormone receptor β (THR-β) agonist with an EC50 of 0.21 μM, shows 28-fold selective for THR-β over THR-α in a functional assay.

Storage Conditions

3 years -20°C powder

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