VcMMAE
Product Specifications
CAS Number
646502-53-6
Synonyms
Mc-vc-PAB-MMAE
Target
Microtubule Associated
Applications
Cytoskeletal Signaling
Smiles
CCC (C) C (C (CC (=O) N1CCCC1C (C (C) C (=O) NC (C) C (C2=CC=CC=C2) O) OC) OC) N (C) C (=O) C (C (C) C) NC (=O) C (C (C) C) N (C) C (=O) OCC3=CC=C (C=C3) NC (=O) C (CCCNC (=O) N) NC (=O) C (C (C) C) NC (=O) CCCCCN4C (=O) C=CC4=O
Molecular Formula
C68H105N11O15
Additionnal Information
VcMMAE (mc-vc-PAB-MMAE), a MMAE derivative with valine-citrulline (Vc) linker, is an Drug-linker Conjugate for antibody-drug conjugate (ADC) with potent antitumor activity. MMAE is a synthetic antineoplastic agent and can be efficiently released from VcMMAE in vitro and exert cytotoxic activity.
Storage Conditions
3 years -20°C powder
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