B-Raf inhibitor 1 (Compound 13) dihydrochloride
Product Specifications
CAS Number
1191385-19-9
Target
Raf
Applications
MAPK
Smiles
CC1=C (C2=C (C=C1) C (=NC=C2) NC3=CC=C (C=C3) Cl) NC4=C (C=CC=N4) C5=C6C (=NC=N5) N=CN6.Cl.Cl
Molecular Formula
C26H21Cl3N8
Additionnal Information
B-Raf inhibitor 1 (Compound 13) is a type IIA Raf inhibitor which bind to the DFG-out conformation with ki of 1 nM,1 nM, and 0.3 nM for B-Raf (WT), B-Raf (V600E) and C-Raf, respectively.
Storage Conditions
3 years -20°C powder
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