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Seladelpar

Product Specifications

CAS Number

851528-79-5

Synonyms

MBX-8025

Target

PPAR

Applications

DNA Damage/DNA Repair

Molecular Formula

C21H23F3O5S

Additionnal Information

Seladelpar (MBX-8025) is a potent and selective agonist of peroxisome proliferator–activated receptor-delta (PPAR-δ) with EC50 of 2 nM for human PPAR-δ. MBX-8025 enhances insulin sensitivity, counters dyslipidemia, and reduces hepatic storage of lipotoxic lipids, thereby ameliorating NASH pathology in obese diabetic mice.

Storage Conditions

2 years -20°C liquid

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