APY29
Product Specifications
CAS Number
1216665-49-4
Target
IRE1
Applications
ER stress & UPR
Smiles
C1CC1C2=CC (=NN2) NC3=NC (=NC=C3) NC4=CC5=C (C=C4) N=CN5
Molecular Formula
C17H16N8
Additionnal Information
APY29 is a type I kinase inhibitor of IRE1α that binds to the ATP-binding site on IRE1α and inhibits its autophosphorylation (IC50 = 280 nM) and enhances its RNase function (EC50 = 460 nM) .
Storage Conditions
3 years -20°C powder
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